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Lotensin (Generic)
Lotensin (Benazepril) is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Benazepril is used to treat high blood pressure (hypertension).

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Uses

This drug belongs to a group of medications called ACE inhibitors. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
OTHER USES: This medication may also be used to help protect the kidneys from damage due to diabetes and with other drugs (e.g., "water pills"/diuretics, digoxin) to treat congestive heart failure.

How to take

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take each dose with a full glass of water.
Benazepril can be taken with or without food.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking benazepril. Drink plenty of water each day while you are taking this medication.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking benazepril. You may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Side effects

Benazepril is generally well tolerated and side effects are usually mild and transient. A dry, persistent cough has been reported with the use of benazepril and other ACE inhibitors. Coughing resolves after discontinuing the medication. Other side effects are rare and include abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, loss of taste, loss of appetite, nausea and vomiting, easy bruising or bleeding, chest pain, chills, difficulty breathing, severe dizziness or fainting, fever, numbness or tingling in the hands or feet, rash, and a sore or swollen throat. In rare instances, liver dysfunction and skin yellowing (jaundice) have been reported with ACE inhibitors.

Precaution

Some medical conditions may interact with Benazepril. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:
·1 if you are pregnant, planning to become pregnant, or are breast-feeding.
·2 if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
·3 if you have allergies to medicines, foods, or other substances.
·4 if you have or have ever had liver or kidney problems, kidney transplantation, or diabetes.
·5 if you have systemic lupus erythematosus (SLE or lupus), scleroderma or a collagen vascular disease (ask your doctor if you are not sure), bone marrow suppression, low blood counts, low blood pressure, low blood sodium, high blood potassium, or narrowing or hardening of the arteries of the brain, or if you are dehydrated.
·6 if you are scheduled to have surgery or to receive anesthesia or kidney dialysis.

Drug interactions

Benazepril should not be taken by people with a known allergy to ACE inhibitors. Swelling of the facial tissues and even the upper airways has been reported with ACE inhibitors on very rare occasions, and can lead to serious breathing difficulties. Benazepril can interact with diuretics (water pills) and other blood pressure medicines to cause an excessive drop in blood pressure, which can result in symptoms of weakness, dizziness, and lightheadedness. Worsening of kidney function has been reported with ACE inhibitors, especially in patients with severe heart failure or pre-existing kidney disease. Combining benazepril with potassium supplements, potassium containing salt substitutes, and potassium conserving diuretics such as amiloride (Moduretic), spironolactone (Aldactone), and triamterene (Dyazide, Maxzide), can lead to dangerously high blood levels of potassium. Indomethacin (Indocin) and possibly other anti-inflammatory medications may decrease the blood pressure lowering effect of benazepril.
In rare instances, low white blood cell counts have been reported with the use of another ACE inhibitor. Low white blood cells increase the patient's risk of infections. When taken with lithium, benazepril can increase lithium to toxic levels in the blood. Safe use in children is not established. It is not habit forming.

Missed dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom. Keep away from children and pets.